Federal solicitation · DARPA-SN-26-67 · back to recent

Research Opportunity: DNA-Protein Epigenetic Chemistry Engineering (D-PECHE)

Agency: DEPT OF DEFENSE
Status: Closed
Response deadline: June 24, 2026
Posted: May 6, 2026
Set-aside: Not listed
NAICS: 541714
Source: View on SAM.gov
Last checked: 2026-06-25

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Solicitation description

The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals to demonstrate proof-of-concept for novel mechanisms for writing and erasing epigenetic base modifications in DNA. Mechanisms capable of modifying the epigenome offer new opportunities to control DNA-protein interactions and to study the functions and applications of rare or novel epigenetic modifications. This research opportunity will result in demonstrations of novel technologies to modify nucleic acids in vitro.

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